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Cells & molecules

Meiosis

Cell biology · Cell division

3D cutaway of the meiosis Open the interactive 3D model →

Why do brothers and sisters with the same two parents never turn out identical?

You got one set of chromosomes from your mother and one from your father. To make eggs or sperm, a cell divides twice, shuffling and swapping pieces of those two sets so every egg or sperm gets just one set — and a different mix each time. This special division is called meiosis.

Meiosis is the pair of divisions that turns one diploid germ cell into four haploid cells, halving the chromosome number for sexual reproduction. In meiosis I homologous chromosomes pair, recombine and separate; in meiosis II, without further DNA replication, sister chromatids separate.

Key facts

Divisions
2 (meiosis I reductional, meiosis II equational) after one S phase
Products
4 haploid cells (sperm); 1 egg + 2–3 polar bodies in oogenesis
Human chromosome number
2n = 46 → n = 23
Crossovers in humans
≈ 2–3 per bivalent; ≈ 50–70 per meiosis
Assortment combinations (humans)
2²³ ≈ 8.4 million per parent, before crossing over
Duration
Human male ≈ 3–4 weeks; female prophase I arrest lasts 12–50 years

Parts you can explore (11)

In the 3D model

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