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Bone & osteon

Anatomy · Skeletal system · Histology

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How can a thighbone light enough to run on carry several times your body weight with every stride?

Bone is not solid rock: it is living tissue made of tough protein fibres hardened with calcium minerals. The outside is a dense shell, while the ends are filled with a light honeycomb of struts lined up exactly along the directions the bone gets pushed and pulled. Living cells inside keep rebuilding it, adding bone where it is loaded and removing it where it is not.

Bone is a living composite of collagen and hydroxyapatite arranged as dense compact bone, built from cylindrical osteons, and porous spongy bone whose trabeculae align with the loads they carry. Cells embedded in and lining this matrix continually remodel it, so the skeleton adapts its architecture to mechanical demand.

Key facts

Matrix composition (by mass)
≈ 60–70% mineral (hydroxyapatite), 20–30% organic (mostly type I collagen), ≈ 10% water
Compact vs spongy
≈ 80% / 20% of skeletal mass
Osteon diameter
≈ 150–250 µm; central canal ≈ 50 µm
Lamella thickness
≈ 3–7 µm
Adult remodelling rate
≈ 10% of the skeleton per year
Hip contact force, walking
≈ 2.5–3× body weight

Parts you can explore (12)

In the 3D model

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